RESUMO
INTRODUCTION: PRP is a rare entity of unknown etiopathogenesis. Lack of management guidelines makes it a challenge for clinicians. OBJECTIVE: To add our experience to increase evidence about PRP. METHODS: We performed a retrospective, descriptive and multicentric study of 65 patients with PRP, being the largest European case series of patients with PRP. RESULTS: PRP was more frequent in male patients with an average age of 51 years, but erythrodermic forms presented in older patients (average age 61 years). Six (75%) paediatric patients and ten (60%) non-erythrodermic adults controlled their disease with topical corticosteroids. On the contrary, 26 (68%) erythrodermic patients required biologic therapy as last and effective therapy line requiring an average of 6.5 months to achieve complete response. CONCLUSION: Our study showed a statistical difference in terms of outcome and response to treatment between children or patients with limited disease and patients who develop erythroderma.
Assuntos
Neoplasias de Bainha Neural , Neurotecoma , Neoplasias Cutâneas , Biomarcadores Tumorais , Humanos , Lactente , Masculino , Neoplasias de Bainha Neural/diagnóstico , Neoplasias de Bainha Neural/patologia , Neurotecoma/diagnóstico , Neurotecoma/patologia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologiaRESUMO
No disponible
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Humanos , Feminino , Pessoa de Meia-Idade , Dermatite/complicações , Dermatite/tratamento farmacológico , Progesterona/administração & dosagem , Corticosteroides/administração & dosagem , Ciclo Menstrual , Eritema/complicações , Dermatopatias/induzido quimicamente , Dermatopatias/complicaçõesRESUMO
No disponible
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Humanos , Feminino , Pessoa de Meia-Idade , Febre Familiar do Mediterrâneo/complicações , Febre Familiar do Mediterrâneo/diagnóstico , Eritema/complicações , Edema/complicações , Edema/terapia , Diagnóstico Diferencial , Colchicina/uso terapêutico , Febre Familiar do Mediterrâneo/microbiologia , Febre Familiar do Mediterrâneo/terapia , Amiloidose Familiar/complicações , Amiloidose Familiar/terapiaAssuntos
Febre Familiar do Mediterrâneo/diagnóstico , Idoso , Derme/patologia , Edema/etiologia , Edema/patologia , Eritema/etiologia , Eritema/patologia , Febre Familiar do Mediterrâneo/genética , Febre Familiar do Mediterrâneo/patologia , Feminino , Humanos , Linfócitos/patologia , Neutrófilos/patologia , Pirina/genética , Pele/patologiaRESUMO
No disponible
Assuntos
Humanos , Masculino , Adulto , Ceratose/etiologia , Ceratose/patologia , Ceratose/terapia , Biópsia/instrumentação , Biópsia/métodos , Biópsia , Dermatite Perioral/terapia , Ceratodermia Palmar e Plantar/terapiaRESUMO
Fundamento: El eccema labial es un problema poco frecuente en las Unidades de Eccema de Contacto (UEC). Hasta el momento han sido publicadas escasas series que muestren el perfil de estos pacientes y las causas de su eccema, ninguna de ellas española. El objetivo de este estudio fue el de analizar el perfil epidemiológico de los pacientes que acuden a la UEC en nuestro entorno, los diagnósticos principales y los alérgenos relevantes. Material y métodos: Se realizó una revisión retrospectiva de los pacientes remitidos a la UEC en el periodo 2005-2014. Se realizaron pruebas epicutáneas con la serie estándar ampliada del Grupo Español de Investigación en Dermatitis Alérgica de contacto (GEIDAC), productos propios y otras baterías complementarias. Resultados: En los 78 pacientes estudiados, los diagnósticos más frecuentes fueron la dermatitis de contacto alérgica y la dermatitis atópica. Los alérgenos relevantes más frecuentes fueron los cosméticos y los fármacos tópicos. Conclusiones: Es fundamental estudiar a los pacientes con eccema labial con pruebas epicutáneas para poder filiar correctamente su etiología y según esto, realizar un tratamiento más adecuado (AU)
Background: Lip eczema is an infrequent problem in Contact Dermatitis Units (CDU). Very few series have been published to date that show the profiles of such patients and the causes of their eczemas, and none are Spanish. The goal of this study was to analyze the epidemiological profile of the patients who attend a CDU in our setting, the main diagnoses and the relevant allergens. Methods: A retrospective review was made of the patients referred to the CDU in the 2005-2014 period. Patch tests were carried out with the extended standard series of the Spanish Research Group on Allergic Contact Dermatitis (Grupo Español de Investigación en Dermatitis Alérgica de contacto - GEIDAC), our own products and other complementary sets. Results: The most frequent diagnoses in the 78 patients studied were allergic contact dermatitis and atopic dermatitis. The most frequent relevant allergens were cosmetics and topical medications. Conclusions: It is essential to study the patients with lip eczema with patch tests to be able to correctly determine their etiology and accordingly to carry out the most suitable treatment (AU)
Assuntos
Humanos , Masculino , Feminino , Dermatite Atópica/complicações , Dermatite Atópica/patologia , Testes do Emplastro/enfermagem , Dermatite Alérgica de Contato/genética , Hipersensibilidade/sangue , Cosméticos/toxicidade , Queilite/patologia , Dermatite Atópica/genética , Testes do Emplastro/métodos , Testes do Emplastro/normas , Dermatite Alérgica de Contato/classificação , Dermatite Alérgica de Contato/complicações , Hipersensibilidade/metabolismo , Cosméticos/síntese química , Preparações Farmacêuticas/metabolismo , Queilite/complicações , Queilite/diagnósticoRESUMO
BACKGROUND: Tea tree oil is an essential oil, whose use is increasing in our setting, due both to its supposed medicinal effects and to its aromatic properties. We describe our experience with allergic contact dermatitis following the application of this oil. MATERIAL AND METHODS: Five patients in the last 5 years (0.4% of all the patients studied in specialized consultation) reacted to a 5% concentration of tea tree oil in Vaseline. RESULTS: All the patients presented strong reactions, and in all cases these were considered relevant. Three of them also reacted to oxidized d-limonene, one of the components of tea tree oil, which is present in our standard series. CONCLUSIONS: Different cases have been described in the literature on allergic contact dermatitis due to tea tree oil, but until recently it was infrequent in our setting. With the increased popularity of alternative and natural therapies we have witnessed several cases of sensitization to this essential oil, which had been used to treat several supposedly "infectious" skin diseases, but which were very probably different forms of dermatitis.
Assuntos
Dermatite Alérgica de Contato/etiologia , Óleo de Melaleuca/efeitos adversos , Administração Tópica , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Óleo de Melaleuca/administração & dosagemRESUMO
Fundamento: El aceite de árbol de té es un aceite esencial, cuyo uso está aumentando en nuestro medio, tanto por sus supuestos efectos medicinales, como por sus propiedades aromáticas. Se describe nuestra experiencia en dermatitis alérgica de contacto tras la aplicación de este aceite. Material y Métodos: Cinco pacientes en los últimos 5 años (0,4% de todos los pacientes estudiados en consulta especializada) reaccionaron a una concentración de 5% de aceite de árbol de té en vaselina. Resultados: Todos los pacientes presentaron reacciones fuertes, y en todos los casos éstas fueron consideradas relevantes. Tres de ellos reaccionaron también a d-limoneno oxidado, uno de los componentes del aceite de árbol de té, que está presente en nuestra serie estándar. Conclusiones: Se han descrito diversos casos en la literatura de dermatitis alérgica de contacto al aceite de árbol de té, pero hasta hace poco ha sido infrecuente en nuestro medio. Con el aumento de popularidad de terapias alternativas y naturales hemos sido testigos de varios casos de sensibilización a este aceite esencial, que había sido utilizado para tratar varias enfermedades de la piel supuestamente "infecciosas", pero que eran muy probablemente diferentes formas de dermatitis (AU)
Background: Tea tree oil is an essential oil, whose use is increasing in our setting, due both to its supposed medicinal effects and to its aromatic properties. We describe our experience with allergic contact dermatitis following the application of this oil. Material and methods: Five patients in the last 5 years (0.4% of all the patients studied in specialized consultation) reacted to a 5% concentration of tea tree oil in Vaseline. Results: All the patients presented strong reactions, and in all cases these were considered relevant. Three of them also reacted to oxidized d-limonene, one of the components of tea tree oil, which is present in our standard series. Conclusions: Different cases have been described in the literature on allergic contact dermatitis due to tea tree oil, but until recently it was infrequent in our setting. With the increased popularity of alternative and natural therapies we have witnessed several cases of sensitization to this essential oil, which had been used to treat several supposedly "infectious" skin diseases, but which were very probably different forms of dermatitis (AU)
Assuntos
Humanos , Masculino , Feminino , Adolescente , Pessoa de Meia-Idade , Dermatite Alérgica de Contato/diagnóstico , Óleo de Melaleuca/efeitos adversos , Terapias Complementares/efeitos adversos , Anti-Infecciosos Locais/efeitos adversosRESUMO
BACKGROUND: Lip eczema is an infrequent problem in Contact Dermatitis Units (CDU). Very few series have been published to date that show the profiles of such patients and the causes of their eczemas, and none are Spanish. The goal of this study was to analyze the epidemiological profile of the patients who attend a CDU in our setting, the main diagnoses and the relevant allergens. METHODS: A retrospective review was made of the patients referred to the CDU in the 2005-2014 period. Patch tests were carried out with the extended standard series of the Spanish Research Group on Allergic Contact Dermatitis (Grupo Español de Investigación en Dermatitis Alérgica de contacto - GEIDAC), our own products and other complementary sets. RESULTS: The most frequent diagnoses in the 78 patients studied were allergic contact dermatitis and atopic dermatitis. The most frequent relevant allergens were cosmetics and topical medications. CONCLUSIONS: It is essential to study the patients with lip eczema with patch tests to be able to correctly determine their etiology and accordingly to carry out the most suitable treatment.
